Scientists shed new light on how early stage breast cancer spreads to other organs – CNBC
A consultant analyzing a mammogram.
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Scientists have shed new light on how early stage breast cancer spreads to other organs undetected, which can cause fatal metastatic cancer in some women years later.
Before a breast cancer tumor is even detected, cells that are not yet malignant can spread to other organs where they lie dormant and don't replicate, according to new research led by Maria Soledad Sosa, a professor at Mount Sinai's Tisch Cancer Institute in New York City.
The NR2F1 gene normally prevents pre-malignant cells from spreading to other parts of the body.
Sosa and a team of scientists found that a cancer gene, HER2, suppresses the NR2F1 gene, allowing pre-cancerous cells to move to other organs of the body whe...