A Single Hormone That Can Help Increase Lifespan Has Been Identified in Mice – ScienceAlert
Low-protein diets appear to have incredible benefits for the health and lifespans of rodents, fruit flies, and yeast.
A new study in mice has now identified a single hormone that is essential for these curious anti-aging effects.
The hormone is called fibroblast growth factor 21 (FGF21), and it is secreted by the liver.
In recent years, studies have shown that FGF21 responds to protein restriction in male mice, improving energy expenditure and glucose tolerance while reducing body weight.
Now, the same team of researchers has found FGF21 is required for the anti-aging effects, too.
"Indeed, mice that are FGF21 deficient are not only resistant to the health [benefits] of [protein restriction], but they also exhibit early-onset weight loss, increased frailty, and reduced lifespan whe...