More than 80 percent of the current cases are linked to the city of Hebron, which began to shut down on Wednesday evening.
Mr. Milhim said that the five-day lockdown could be extended and called on Palestinians to follow social distancing guidelines and wear masks, warning that there would be consequences for those who did not comply.
Reporting was contributed by Rachel Abrams, Livia Albeck-Ripka, Aliza Aufrichtig, Julie Bosman, Benedict Carey, Ben Casselman, Stephen Castle, Emily Cochrane, Michael Cooper, Jill Cowan, Steven Erlanger, Richard Fausset, Luis Ferré-Sadurní, Kimiko de Freytas-Tamura, Thomas Fuller, Jenny Gross, Jack Healy, Makiko Inoue, Annie Karni, Isabella Kwai, Ernesto Londoño, Patricia Mazzei, Mark Mazzetti, Giulia McDonnell Nieto del Rio, Jesse McKinley, Sarah Mervosh, Anna Momigliano, Monika Pronczuk, Adam Rasgon, Motoko Rich, Amanda Rosa, Nelson D. Schwartz, Dionne Searcey, Ed Shanahan, Eliza Shapiro, Mitch Smith, Jim Tankersley, Sabrina Tavernise, Hisako Ueno, David Waldstein, Caryn A. Wilson, Edward Wong, Sameer Yasir and Karen Zraick.