Month: January 2022

Excessive social media use was linked with poorer physical health in a new study of students. Those who used it more had higher levels of a blood protein which indicates chronic inflammation. First author David Lee said there is "an undeniable link between mental health and physical health." Loading Something is loading. College students who used social media "e...

According to the eClinicalMedicine journal, if the eGFR equation did not include a race adjustment, 31,000 more Black Americans would become eligible for a kidney transplant, 300,000 more would qualify for a nephrologist referral, and 3.3 million more would reach the threshold for stage 3 chronic kidney disease. “As medical students, we’re explicitly taught to think about race in this way, that there’s some underlying biological difference at a population level,” Jennifer Tsai, a resident in Yale’s Department of Emergency Medicine and lead author of the study. “As we show in this study, there are many reasons why we think this is not valid.” So where did all of this come from? Why is race a factor in the eGFR? Well, the medical community has wrongly claimed for decades that Black ...

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It all started with genetic data. A gene here, a gene there. Eventually the story became clearer: If scientists are to one day find a cure for Alzheimer's disease, they should look to the immune system. Over the past couple decades, researchers have identified numerous genes involved in various immune system functions that may also contribute to Alzheimer's. Some of the prime suspects are genes that control immune cells called microglia, now the focus of intense research in developing new Alzheimer's drugs. Microglia are amoeba-like cells that scour the brain for injuries and invaders. They help clear dead or impaired brain cells and literally gobble up invading microbes. Without them, we'd be in trouble. In a no...

The trial, titled IAVI G002, is being conducted in partnership IAVI, a nonprofit scientific research organization. It is testing a vaccine that delivers HIV-specific antigens to the body with the goal of inducing an immune response. These antigens were initially developed by researchers at IAVI and Scripps Research, led by Dr. William Schief. In a "proof-of-concept" trial last year, the research team found the HIV antigens produced the desired immune response in 97% of participants. The current trial builds on the previous one by testing the primary version of the vaccine and also a booster version, and by employing Moderna's mRNA technology, which was previously used to create a successful Covid-19 vaccine. "We are tremendously excited to be advancing this new direction in HIV va...