Johnson & Johnson HIV vaccine trial fails mid-stage study – ABC News
In yet another setback in the decadeslong scientific quest for an HIV vaccine, a Johnson & Johnson HIV vaccine candidate failed to reduce the risk of infection in a clinical trial among women in southern Africa. The would-be vaccine uses the same underlying technology used successfully for COVID-19 and Ebola viruses, but this recent high-profile failure is another example of immense challenge of creating a vaccine against HIV.
The trial, called Imbokodo, was co-sponsored by the Bill & Melinda Gates Foundation and the U.S. National Institutes of Health. It included more than 2,600 women living in five African countries where women and girls have a high risk of HIV infection.
The vaccine was safe, researchers said, but ultimately, efficacy was only 25% -- meaning people who receive...